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The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development

The embryonic expression of COUP-TFII, an orphan nuclear receptor, suggests that it may participate in mesenchymal–epithelial interactions required for organogenesis. Targeted deletion of the COUP-TFII gene results in embryonic lethality with defects in angiogenesis and heart development. COUP-TFII...

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Bibliographic Details
Main Authors: Pereira, Fred A., Qiu, Yuhong, Zhou, Ge, Tsai, Ming-Jer, Tsai, Sophia Y.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC316637/
https://ncbi.nlm.nih.gov/pubmed/10215630
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