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Ranking Candidate Disease Genes from Gene Expression and Protein Interaction: A Katz-Centrality Based Approach

Many diseases have complex genetic causes, where a set of alleles can affect the propensity of getting the disease. The identification of such disease genes is important to understand the mechanistic and evolutionary aspects of pathogenesis, improve diagnosis and treatment of the disease, and aid in...

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Detalhes bibliográficos
Main Authors: Zhao, Jing, Yang, Ting-Hong, Huang, Yongxu, Holme, Petter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166320/
https://ncbi.nlm.nih.gov/pubmed/21912686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024306
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