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Sox1 directly regulates the γ-crystallin genes and is essential for lens development in mice

γ-Crystallins are major structural components of the lens fiber cells in amphibians and mammals. Many dominant inherited cataracts in humans and mice have been shown to map within the γ-crystallin gene cluster. Several transcription factors, including PAX6 and SOX proteins, have been suggested as ca...

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Autori principali: Nishiguchi, Seiji, Wood, Heather, Kondoh, Hisato, Lovell-Badge, Robin, Episkopou, Vasso
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC316632/
https://ncbi.nlm.nih.gov/pubmed/9512512
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