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Polymorphisms in the α4 Integrin of Neotropical Primates: Insights for Binding of Natural Ligands and HIV-1 gp120 to the Human α4β7

The α4 integrin subunit associates with β7 and β1 and plays important roles in immune function and cell trafficking. The gut-homing receptor α4β7 has been recently described as a new receptor for HIV. Here, we describe polymorphisms of ITGA4 gene in New World primates (NWP), and tested their impact...

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Detaylı Bibliyografya
Asıl Yazarlar: Darc, Mirela, Hait, Sabrina H., Soares, Esmeralda A., Cicala, Claudia, Seuanez, Hector N., Machado, Elizabeth S., Arthos, James A., Soares, Marcelo A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166318/
https://ncbi.nlm.nih.gov/pubmed/21912696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024461
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