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Reduced Expression of Brain-Enriched microRNAs in Glioblastomas Permits Targeted Regulation of a Cell Death Gene

Glioblastoma is a highly aggressive malignant tumor involving glial cells in the human brain. We used high-throughput sequencing to comprehensively profile the small RNAs expressed in glioblastoma and non-tumor brain tissues. MicroRNAs (miRNAs) made up the large majority of small RNAs, and we identi...

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Hlavní autoři: Skalsky, Rebecca L., Cullen, Bryan R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166303/
https://ncbi.nlm.nih.gov/pubmed/21912681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024248
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