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Synthesis and Iron Sequestration Equilibria of Novel Exocyclic 3-Hydroxy-2-pyridinone Donor Group Siderophore Mimics

The synthesis of a novel class of exocyclic bis- and tris-3,2-hydroxypyridinone (HOPO) chelators built on N(2) and N(3) aza-macrocyclic scaffolds and the thermodynamic solution characterization of their complexes with Fe(III) are described. The chelators for this study were prepared by reaction of e...

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Autori principali: Harrington, James M., Chittamuru, Sumathi, Dhungana, Suraj, Jacobs, Hollie K., Gopalan, Aravamudan S., Crumbliss, Alvin L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166231/
https://ncbi.nlm.nih.gov/pubmed/20715813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic902595c
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