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A Method for Efficient Calculation of Diffusion and Reactions of Lipophilic Compounds in Complex Cell Geometry

A general description of effects of toxic compounds in mammalian cells is facing several problems. Firstly, most toxic compounds are hydrophobic and partition phenomena strongly influence their behaviour. Secondly, cells display considerable heterogeneity regarding the presence, activity and distrib...

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Detalhes bibliográficos
Main Authors: Dreij, Kristian, Chaudhry, Qasim Ali, Jernström, Bengt, Morgenstern, Ralf, Hanke, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166132/
https://ncbi.nlm.nih.gov/pubmed/21912588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023128
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