Synergistic effect of Bcl2, Myc and Ccnd1 transforms mouse primary B cells into malignant cells

BACKGROUND: A synergistic effect resulting from a combination of BCL2 and MYC or MYC and CCND1 has been implicated in human B-cell lymphomas. Although the identification of other cooperative genes involved is important, our present understanding of such genes remains scant. The objective of this stu...

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Main Authors: Nakagawa, Masao, Tsuzuki, Shinobu, Honma, Keiichiro, Taguchi, Osamu, Seto, Masao
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2011
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166102/
https://ncbi.nlm.nih.gov/pubmed/21606168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.041053
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