Identification of KIF3A as a Novel Candidate Gene for Childhood Asthma Using RNA Expression and Population Allelic Frequencies Differences

BACKGROUND: Asthma is a chronic inflammatory disease with a strong genetic predisposition. A major challenge for candidate gene association studies in asthma is the selection of biologically relevant genes. METHODOLOGY/PRINCIPAL FINDINGS: Using epithelial RNA expression arrays, HapMap allele frequen...

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Hauptverfasser: Butsch Kovacic, Melinda, Biagini Myers, Jocelyn M., Wang, Ning, Martin, Lisa J., Lindsey, Mark, Ericksen, Mark B., He, Hua, Patterson, Tia L., Baye, Tesfaye M., Torgerson, Dara, Roth, Lindsey A., Gupta, Jayanta, Sivaprasad, Umasundari, Gibson, Aaron M., Tsoras, Anna M., Hu, Donglei, Eng, Celeste, Chapela, Rocío, Rodríguez-Santana, José R., Rodríguez-Cintrón, William, Avila, Pedro C., Beckman, Kenneth, Seibold, Max A., Gignoux, Chris, Musaad, Salma M., Chen, Weiguo, Burchard, Esteban González, Khurana Hershey, Gurjit K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166061/
https://ncbi.nlm.nih.gov/pubmed/21912604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023714
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