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RNAi-independent role for Argonaute2 in CTCF/CP190 chromatin insulator function

A major role of the RNAi pathway in Schizosaccharomyces pombe is to nucleate heterochromatin, but it remains unclear whether this mechanism is conserved. To address this question in Drosophila, we performed genome-wide localization of Argonaute2 (AGO2) by chromatin immunoprecipitation (ChIP)-seq in...

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Detalhes bibliográficos
Main Authors: Moshkovich, Nellie, Nisha, Parul, Boyle, Patrick J., Thompson, Brandi A., Dale, Ryan K., Lei, Elissa P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165934/
https://ncbi.nlm.nih.gov/pubmed/21852534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.16651211
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