Specific isoforms of Squid, a Drosophila hnRNP, perform distinct roles in Gurken localization during oogenesis

Heterogeneous nuclear RNA-binding proteins, hnRNPs, have been implicated in nuclear export of mRNAs in organisms from yeast to humans. A germ-line mutation in a Drosophila hnRNP, Squid (Sqd)/hrp40, causes female sterility as a result of mislocalization of gurken (grk) mRNA during oogenesis. Alternat...

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Détails bibliographiques

Publié dans:	Genes Dev
Auteurs principaux:	Norvell, Amanda, Kelley, Richard L., Wehr, Kristina, Schüpbach, Trudi
Format:	Artigo
Langue:	Inglês
Publié:	Cold Spring Harbor Laboratory Press 1999
Sujets:	Research Paper
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316593/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10197986/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.7.864
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