Analyses of In Vitro Nonenzymatic Glycation of Normal and Variant Hemoglobins by MALDI-TOF Mass Spectrometry

MALDI-TOF mass spectrometry is used here to differentiate different glycoisoforms of normal and variant hemoglobins (Hbs) in nonenzymatic in vitro glycation. Single, double, and/or multiple glycation of the α-globin, β-globin, and/or γ-globin is observed. Different glycation rates are observed for v...

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Autores principales: Lee, Bao-Shiang, Jayathilaka, G. D. Lasanthi P., Huang, Jin-Sheng, Vida, Loyda N., Honig, George R., Gupta, Shalini
Formato: Artigo
Lenguaje:Inglês
Publicado: Association of Biomolecular Resource Facilities 2011
Materias:
Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165857/
https://ncbi.nlm.nih.gov/pubmed/21966256
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