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Adenovirus E1A Directly Targets the E2F/DP-1 Complex

Deregulation of the cell cycle is of paramount importance during adenovirus infection. Adenovirus normally infects quiescent cells and must initiate the cell cycle in order to propagate itself. The pRb family of proteins controls entry into the cell cycle by interacting with and repressing transcrip...

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Autores principales: Pelka, Peter, Miller, Matthew S., Cecchini, Matthew, Yousef, Ahmed F., Bowdish, Dawn M., Dick, Fred, Whyte, Peter, Mymryk, Joe S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165805/
https://ncbi.nlm.nih.gov/pubmed/21715488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00539-11
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