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SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish

SCL/Tal-1 is a transcription factor necessary for hematopoietic stem cell differentiation. Although SCL is also expressed in endothelial and neural progenitors, SCL function in these cells remains unknown. In the zebrafish mutant cloche (clo), SCL expression is nearly abolished in hematopoietic and...

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Auteurs principaux: Liao, Eric C., Paw, Barry H., Oates, Andrew C., Pratt, Stephen J., Postlethwait, John H., Zon, Leonard I.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC316577/
https://ncbi.nlm.nih.gov/pubmed/9499398
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