Deletion of the Monkeypox Virus Inhibitor of Complement Enzymes Locus Impacts the Adaptive Immune Response to Monkeypox Virus in a Nonhuman Primate Model of Infection

Monkeypox virus (MPXV) is an orthopoxvirus closely related to variola virus, the causative agent of smallpox. Human MPXV infection results in a disease that is similar to smallpox and can also be fatal. Two clades of MPXV have been identified, with viruses of the central African clade displaying mor...

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Detalhes bibliográficos
Main Authors: Estep, Ryan D., Messaoudi, Ilhem, O'Connor, Megan A., Li, Helen, Sprague, Jerald, Barron, Alexander, Engelmann, Flora, Yen, Bonnie, Powers, Michael F., Jones, John M., Robinson, Bridget A., Orzechowska, Beata U., Manoharan, Minsha, Legasse, Alfred, Planer, Shannon, Wilk, Jennifer, Axthelm, Michael K., Wong, Scott W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165757/
https://ncbi.nlm.nih.gov/pubmed/21752919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00199-11
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