Herpes Simplex Virus 1 Protein Kinase Us3 and Major Tegument Protein UL47 Reciprocally Regulate Their Subcellular Localization in Infected Cells

Us3 is a serine-threonine protein kinase encoded by herpes simplex virus 1 (HSV-1). We have identified UL47, a major virion protein, as a novel physiological substrate of Us3. In vitro kinase assays and systematic analysis of mutations at putative Us3 phosphorylation sites near the nuclear localizat...

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Detalhes bibliográficos
Main Authors: Kato, Akihisa, Liu, Zhuoming, Minowa, Atsuko, Imai, Takahiko, Tanaka, Michiko, Sugimoto, Ken, Nishiyama, Yukihiro, Arii, Jun, Kawaguchi, Yasushi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165750/
https://ncbi.nlm.nih.gov/pubmed/21734045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00845-11
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