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Suppression of STAT-1 Expression by Human Papillomaviruses Is Necessary for Differentiation-Dependent Genome Amplification and Plasmid Maintenance

High-risk human papillomaviruses (HPVs) infect stratified epithelia to establish persistent infections that maintain low-copy-number episomes in infected basal cells. Amplification of viral genomes occurs upon keratinocyte differentiation, followed by virion synthesis. During persistent HPV infectio...

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Detalhes bibliográficos
Main Authors: Hong, Shiyuan, Mehta, Kavi P., Laimins, Laimonis A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165741/
https://ncbi.nlm.nih.gov/pubmed/21734056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05007-11
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