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Cooperative Transcriptional Activation by Klf4, Meis2, and Pbx1

The Kruppel-like factor Klf4 is implicated in tumorigenesis and maintaining stem cell pluripotency, and Klf4 can both activate and repress gene expression. We show that the Pbx1 and Meis2 homeodomain proteins interact with Klf4 and can be recruited to DNA elements comprising a Klf4 site or GC box, w...

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Bibliografski detalji
Glavni autori: Bjerke, Glen A., Hyman-Walsh, Cathy, Wotton, David
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165729/
https://ncbi.nlm.nih.gov/pubmed/21746878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01456-10
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