The Residue Threonine 82 of DevR (DosR) Is Essential for DevR Activation and Function in Mycobacterium tuberculosis Despite Its Atypical Location

The DevR (DosR) response regulator initiates the bacterial adaptive response to a variety of signals, including hypoxia in in vitro models of dormancy. Its receiver domain works as a phosphorylation-mediated switch to activate the DNA binding property of its output domain. Receiver domains are chara...

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Autors principals: Gautam, Uma Shankar, Sikri, Kriti, Tyagi, Jaya Sivaswami
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165668/
https://ncbi.nlm.nih.gov/pubmed/21764934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.05051-11
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