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A Fail-Safe Mechanism in the Septal Ring Assembly Pathway Generated by the Sequential Recruitment of Cell Separation Amidases and Their Activators

During cytokinesis in Escherichia coli, the peptidoglycan (PG) layer produced by the divisome must be split to promote cell separation. Septal PG splitting is mediated by the amidases: AmiA, AmiB, and AmiC. To efficiently hydrolyze PG, the amidases must be activated by LytM domain factors. EnvC spec...

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Detalhes bibliográficos
Main Authors: Peters, Nick T., Dinh, Thuy, Bernhardt, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165665/
https://ncbi.nlm.nih.gov/pubmed/21764913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00316-11
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