Φορτώνει......
The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity
Biochemical and genetic evidence suggests that the tyrosine kinase activity of c-Abl is tightly regulated in vivo by a cellular factor binding to the Src homology 3 (SH3) domain of Abl. We used the yeast two-hybrid system to identify a gene, PAG, whose protein product (Pag) interacts specifically wi...
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Κύριοι συγγραφείς: | , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Cold Spring Harbor Laboratory Press
1997
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC316562/ https://ncbi.nlm.nih.gov/pubmed/9334312 |
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