Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3′-end formation in yeast

In yeast, four factors (CF I, CF II, PF I, and PAP) are required for accurate pre-mRNA cleavage and polyadenylation in vitro. CF I can be separated further into CF IA and CF IB. Here we show that CF IB is the 73-kD Hrp1 protein. Recombinant Hrp1p made in Escherichia coli provides full CF IB function...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genes Dev
Egile Nagusiak: Kessler, Marco M., Henry, Michael F., Shen, Elisa, Zhao, Jing, Gross, Stefan, Silver, Pamela A., Moore, Claire L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 1997
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316558/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9334319/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.19.2545
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