Attaching and Effacing Bacterial Effector NleC Suppresses Epithelial Inflammatory Responses by Inhibiting NF-κB and p38 Mitogen-Activated Protein Kinase Activation

Enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli are noninvasive attaching and effacing (A/E) bacterial pathogens that cause intestinal inflammation and severe diarrheal disease. These pathogens utilize a type III secretion system to deliver effector proteins into host epitheli...

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Main Authors: Sham, Ho Pan, Shames, Stephanie R., Croxen, Matthew A., Ma, Caixia, Chan, Justin M., Khan, Mohammed A., Wickham, Mark E., Deng, Wanyin, Finlay, B. Brett, Vallance, Bruce A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165486/
https://ncbi.nlm.nih.gov/pubmed/21746856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05033-11
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