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Beta Interferon-Mediated Activation of Signal Transducer and Activator of Transcription Protein 1 Interferes with Rickettsia conorii Replication in Human Endothelial Cells

Infection of the endothelial cell lining of blood vessels with Rickettsia conorii, the causative agent of Mediterranean spotted fever, results in endothelial activation. We investigated the effects of R. conorii infection on the status of the Janus kinase (JAK)-signal transducer and activator of tra...

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Bibliographic Details
Main Authors: Colonne, Punsiri M., Eremeeva, Marina E., Sahni, Sanjeev K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165482/
https://ncbi.nlm.nih.gov/pubmed/21690236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05008-11
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