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Determination of Posaconazole Levels in Toenails of Adults with Onychomycosis following Oral Treatment with Four Regimens of Posaconazole for 12 or 24 Weeks

Pharmacokinetic data from a randomized, parallel-group, multicenter study are presented. Adults with toenail onychomycosis (n = 146) received posaconazole (100 mg, 200 mg, or 400 mg) once daily (QD) for 24 weeks or 400 mg QD for 12 weeks. The posaconazole concentration in the great toenail exhibited...

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Detalhes bibliográficos
Main Authors: Krishna, Gopal, Ma, Lei, Martinho, Monika, Prasad, Pratapa, Wahl, Janice, Tavakkol, Amir
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165322/
https://ncbi.nlm.nih.gov/pubmed/21746944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01302-10
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