In Vitro Activity against Staphylococcus aureus of a Novel Antimicrobial Agent, PRF-119, a Recombinant Chimeric Bacteriophage Endolysin

Antistaphylococcal activity of the novel chimeric endolysin PRF-119 was evaluated with the microdilution method. The MIC(50) and MIC(90) of 398 methicillin-susceptible Staphylococcus aureus isolates were 0.098 μg/ml and 0.391 μg/ml, respectively (range, 0.024 to 0.780 μg/ml). Both the MIC(50) and MI...

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Detalhes bibliográficos
Main Authors: Idelevich, Evgeny A., von Eiff, Christof, Friedrich, Alexander W., Iannelli, Domenico, Xia, Guoqing, Peters, Georg, Peschel, Andreas, Wanninger, Ingrid, Becker, Karsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165309/
https://ncbi.nlm.nih.gov/pubmed/21746950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00217-11
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