Investigation of the Efficacy of Micafungin in the Treatment of Histoplasmosis Using Two North American Strains of Histoplasma capsulatum

Micafungin alone and combined with liposomal amphotericin B was evaluated against two strains of Histoplasma capsulatum. Micafungin was active in vitro against the mold but not the yeast form but was ineffective in vivo. Micafungin appears to be ineffective in treatment of histoplasmosis.

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Detalhes bibliográficos
Main Authors: Hage, Chadi A., Connolly, Patricia, Horan, Daniel, Durkin, Michelle, Smedema, Melinda, Zarnowski, Robert, Smith, Patricia, Wheat, L. Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165286/
https://ncbi.nlm.nih.gov/pubmed/21670186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01681-10
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