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Nuclear import of the Drosophila Rel protein Dorsal is regulated by phosphorylation

In Drosophila, dorsal–ventral polarity is determined by a maternally encoded signal transduction pathway that culminates in the graded nuclear localization of the Rel protein, Dorsal. Dorsal is retained in the cytoplasm by the IκB protein, Cactus. Signal-dependent phosphorylation of Cactus results i...

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Bibliographic Details
Main Authors: Drier, Eric A., Huang, Leslie H., Steward, Ruth
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC316510/
https://ncbi.nlm.nih.gov/pubmed/10072384
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