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BCL-2 family genetic profiling reveals microenvironment-specific determinants of chemotherapeutic response

The Bcl-2 family encompasses a diverse set of apoptotic regulators that are dynamically activated in response various cell intrinsic and extrinsic stimuli. An extensive variety of cell culture experiments have identified effects of growth factors, cytokines and drugs on BCL-2 family functions, but i...

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Detalhes bibliográficos
Main Authors: Pritchard, Justin R., Gilbert, Luke A., Meacham, Corbin E., Ricks, Jennifer L., Jiang, Hai, Lauffenburger, Douglas A., Hemann, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165087/
https://ncbi.nlm.nih.gov/pubmed/21784872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1014
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