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Interaction of the U1 snRNP with nonconserved intronic sequences affects 5′ splice site selection

Intron definition and splice site selection occur at an early stage during assembly of the spliceosome, the complex mediating pre-mRNA splicing. Association of U1 snRNP with the pre-mRNA is required for these early steps. We report here that the yeast U1 snRNP-specific protein Nam8p is a component o...

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Autores principales: Puig, Oscar, Gottschalk, Alexander, Fabrizio, Patrizia, Séraphin, Bertrand
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC316504/
https://ncbi.nlm.nih.gov/pubmed/10072385
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