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Mouse MutS-like protein Msh5 is required for proper chromosome synapsis in male and female meiosis

Members of the mammalian mismatch repair protein family of MutS and MutL homologs have been implicated in postreplicative mismatch correction and chromosome interactions during meiotic recombination. Here we demonstrate that mice carrying a disruption in MutS homolog Msh5 show a meiotic defect, lead...

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Published in:Genes Dev
Main Authors: de Vries, Sandra S., Baart, Esther B., Dekker, Marleen, Siezen, Ariaan, de Rooij, Dirk G., de Boer, Peter, te Riele, Hein
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1999
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Research Paper
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316502/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10072381/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.5.523
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