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Presence of 5-methylcytosine in CpNpG trinucleotides in the human genome

While the methylation machinery of mammalian cells has been shown to be capable of both maintenance and de novo methylation at CpNpG sites, CpNpG methylation in the human genome has not been demonstrated. Here, we report the first observation of 5-methylcytosines in CpNpG triplets in the human genom...

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Autors principals: Lee, Juna, Jang, Se Jin, Benoit, Nicole, Hoque, Mohammad O., Califano, Joseph A., Trink, Barry, Sidransky, David, Mao, Li, Moon, Chulso
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164866/
https://ncbi.nlm.nih.gov/pubmed/20382216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2010.03.013
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