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Presence of 5-methylcytosine in CpNpG trinucleotides in the human genome

While the methylation machinery of mammalian cells has been shown to be capable of both maintenance and de novo methylation at CpNpG sites, CpNpG methylation in the human genome has not been demonstrated. Here, we report the first observation of 5-methylcytosines in CpNpG triplets in the human genom...

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保存先:
書誌詳細
主要な著者: Lee, Juna, Jang, Se Jin, Benoit, Nicole, Hoque, Mohammad O., Califano, Joseph A., Trink, Barry, Sidransky, David, Mao, Li, Moon, Chulso
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164866/
https://ncbi.nlm.nih.gov/pubmed/20382216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2010.03.013
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