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Loss of Inhibitory Neuron AMPA Receptors Contributes to Ataxia and Epilepsy in Stargazer Mice

Stargazer mice are characterized by ataxia and seizures, which resemble the human disorder absence epilepsy. Stargazin, the protein mutated in stargazer mice, promotes the expression and function of neuronal AMPA receptors (AMPARs). However, it is unclear how decreased expression of excitatory AMPAR...

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Autori principali: Menuz, Karen, Nicoll, Roger A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164835/
https://ncbi.nlm.nih.gov/pubmed/18923036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2732-08.2008
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