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Loss of Inhibitory Neuron AMPA Receptors Contributes to Ataxia and Epilepsy in Stargazer Mice

Stargazer mice are characterized by ataxia and seizures, which resemble the human disorder absence epilepsy. Stargazin, the protein mutated in stargazer mice, promotes the expression and function of neuronal AMPA receptors (AMPARs). However, it is unclear how decreased expression of excitatory AMPAR...

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Detalhes bibliográficos
Main Authors: Menuz, Karen, Nicoll, Roger A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164835/
https://ncbi.nlm.nih.gov/pubmed/18923036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2732-08.2008
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