DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

We report the identification of a transcription elongation factor from HeLa cell nuclear extracts that causes pausing of RNA polymerase II (Pol II) in conjunction with the transcription inhibitor 5,6-dichloro-1-β-d-ribofuranosylbenzimidazole (DRB). This factor, termed DRB sensitivity-inducing factor...

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Bibliografiske detaljer

Udgivet i:	Genes Dev
Principais autores:	Wada, Tadashi, Takagi, Toshiyuki, Yamaguchi, Yuki, Ferdous, Anwarul, Imai, Takeshi, Hirose, Susumu, Sugimoto, Seiji, Yano, Keiichi, Hartzog, Grant A., Winston, Fred, Buratowski, Stephen, Handa, Hiroshi
Format:	Artigo
Sprog:	Inglês
Udgivet:	Cold Spring Harbor Laboratory Press 1998
Fag:	Research Paper
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316480/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9450929/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.3.343
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