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Dengue Virus Capsid Protein Binds Core Histones and Inhibits Nucleosome Formation in Human Liver Cells

Dengue virus (DENV) is a member of the Flaviviridae and a globally (re)emerging pathogen that causes serious human disease. There is no specific antiviral or vaccine for dengue virus infection. Flavivirus capsid (C) is a structural protein responsible for gathering the viral RNA into a nucleocapsid...

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Detalhes bibliográficos
Main Authors: Colpitts, Tonya M., Barthel, Sebastian, Wang, Penghua, Fikrig, Erol
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164731/
https://ncbi.nlm.nih.gov/pubmed/21909430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024365
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