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Age-Dependent Recombination Rates in Human Pedigrees

In humans, chromosome-number abnormalities have been associated with altered recombination and increased maternal age. Therefore, age-related effects on recombination are of major importance, especially in relation to the mechanisms involved in human trisomies. Here, we examine the relationship betw...

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Detalhes bibliográficos
Main Authors: Hussin, Julie, Roy-Gagnon, Marie-Hélène, Gendron, Roxanne, Andelfinger, Gregor, Awadalla, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164683/
https://ncbi.nlm.nih.gov/pubmed/21912527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002251
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