Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterning

Zebrafish you-too (yot) mutations interfere with Hedgehog (Hh) signaling during embryogenesis. Using a comparative synteny approach, we isolated yot as a zinc finger transcription factor homologous to the Hh target gli2. Two alleles of yot contain nonsense mutations resulting in carboxy-terminally t...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Karlstrom, Rolf O., Talbot, William S., Schier, Alexander F.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1999
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Research Communication
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316467/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049354/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.4.388
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