HTLV-1 Propels Thymic Human T Cell Development in “Human Immune System” Rag2(-/-) gamma c(-/-) Mice

Alteration of early haematopoietic development is thought to be responsible for the onset of immature leukemias and lymphomas. We have previously demonstrated that Tax(HTLV-1) interferes with ß-selection, an important checkpoint of early thymopoiesis, indicating that human T-cell leukemia virus type...

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Detalhes bibliográficos
Main Authors: Villaudy, Julien, Wencker, Mélanie, Gadot, Nicolas, Gillet, Nicolas A., Scoazec, Jean-Yves, Gazzolo, Louis, Manz, Markus G., Bangham, Charles R. M., Dodon, Madeleine Duc
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164654/
https://ncbi.nlm.nih.gov/pubmed/21909275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002231
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