Sagopilone (ZK-EPO, ZK 219477) for recurrent glioblastoma. A phase II multicenter trial by the European Organisation for Research and Treatment of Cancer (EORTC) Brain Tumor Group

Background: Sagopilone (ZK 219477), a lipophylic and synthetic analog of epothilone B, that crosses the blood–brain barrier has demonstrated preclinical activity in glioma models. Patients and methods: Patients with first recurrence/progression of glioblastoma were eligible for this early phase II a...

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Main Authors: Stupp, R., Tosoni, A., Bromberg, J. E. C., Hau, P., Campone, M., Gijtenbeek, J., Frenay, M., Breimer, L., Wiesinger, H., Allgeier, A., van den Bent, M. J., Bogdahn, U., van der Graaf, W., Yun, H. J., Gorlia, T., Lacombe, D., Brandes, A. A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164435/
https://ncbi.nlm.nih.gov/pubmed/21321091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdq729
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