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Induction of Innate Immune Responses by SIV In Vivo and In Vitro: Differential Expression and Function of RIG-I and MDA5

Interferon-β induction occurs during acute simian immunodeficiency virus (SIV) infection in the brain. We have examined expression and function of cytosolic RNA sensors, retinoic acid inducible gene I (RIG-I), and melanoma differentiation-associated protein 5 (MDA5), in vivo in the brain of our cons...

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Detalhes bibliográficos
Main Authors: Co, Juliene G., Witwer, Kenneth W., Gama, Lucio, Zink, M. Christine, Clements, Janice E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164431/
https://ncbi.nlm.nih.gov/pubmed/21881126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir469
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