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Amino-terminal sequences of σ(N) (σ(54)) inhibit RNA polymerase isomerization

In bacteria, association of the specialized σ(N) protein with the core RNA polymerase subunits forms a holoenzyme able to bind promoter DNA, but unable to melt DNA and initiate transcription unless acted on by an activator protein. The conserved amino-terminal 50 amino acids of σ(N) (Region I) are r...

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Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Cannon, Wendy, Gallegos, María-Trinidad, Casaz, Paul, Buck, Martin
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316430/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9990859/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.3.357
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