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PU.1 regulates PRDI-BF1/Blimp-1 transcription in lymphoma cells

The human positive regulatory domain I binding factor 1 (PRDI-BF1) and its murine homologue Blimp-1 promote differentiation of mature B cells into antibody secreting plasma cells. In contrast, ectopic expression of PRDI-BF1 in lymphoma cells can lead to inhibition of proliferation or apoptosis. Howe...

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Detalhes bibliográficos
Main Authors: Desai, Shruti, Bolick, Sophia C.E., Maurin, Michelle, Wright, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164282/
https://ncbi.nlm.nih.gov/pubmed/19828640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901120
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