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Characterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In Vivo

Ionic liquids (ILs) are a class of salts that are expected to be used as a new source of solvents and for many other applications. Our previous studies revealed that selected ILs, structurally related organic cations, are eliminated exclusively in urine as the parent compound, partially mediated by...

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Autors principals: Cheng, Yaofeng, Martinez-Guerrero, Lucy J., Wright, Stephen H., Kuester, Robert K., Hooth, Michelle J., Sipes, I. Glenn
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164272/
https://ncbi.nlm.nih.gov/pubmed/21646436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.035865
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