The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development

SATB1 is expressed primarily in thymocytes and can act as a transcriptional repressor. SATB1 binds in vivo to the matrix attachment regions (MARs) of DNA, which are implicated in the loop domain organization of chromatin. The role of MAR-binding proteins in specific cell lineages is unknown. We gene...

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Autors principals: Alvarez, John D., Yasui, Dag H., Niida, Hiroyuki, Joh, Tadashi, Loh, Dennis Y., Kohwi-Shigematsu, Terumi
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2000
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC316425/
https://ncbi.nlm.nih.gov/pubmed/10716941
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