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Phase III Study of Molecularly Targeted Adjuvant Therapy in Locally Advanced Urothelial Cancer of the Bladder Based on p53 Status

INTRODUCTION: Retrospective studies suggest that p53 alteration is prognostic for recurrence in patients with urothelial bladder cancer and predictive for benefit from combination methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) adjuvant chemotherapy. PATIENTS AND METHODS: Patients with...

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Detalhes bibliográficos
Main Authors: Stadler, Walter M., Lerner, Seth P., Groshen, Susan, Stein, John P., Shi, Shan-Rong, Raghavan, Derek, Esrig, David, Steinberg, Gary, Wood, David, Klotz, Laurence, Hall, Craig, Skinner, Donald G., Cote, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164246/
https://ncbi.nlm.nih.gov/pubmed/21810677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.34.4028
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