Phase III Study of Molecularly Targeted Adjuvant Therapy in Locally Advanced Urothelial Cancer of the Bladder Based on p53 Status

INTRODUCTION: Retrospective studies suggest that p53 alteration is prognostic for recurrence in patients with urothelial bladder cancer and predictive for benefit from combination methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) adjuvant chemotherapy. PATIENTS AND METHODS: Patients with...

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Hlavní autoři: Stadler, Walter M., Lerner, Seth P., Groshen, Susan, Stein, John P., Shi, Shan-Rong, Raghavan, Derek, Esrig, David, Steinberg, Gary, Wood, David, Klotz, Laurence, Hall, Craig, Skinner, Donald G., Cote, Richard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2011
Témata:
Original Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164246/
https://ncbi.nlm.nih.gov/pubmed/21810677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.34.4028
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