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WISP-1 is a Wnt-1- and β-catenin-responsive oncogene

WISP-1 (Wnt-1 induced secreted protein 1) is a member of the CCN family of growth factors. This study identifies WISP-1 as a β-catenin-regulated gene that can contribute to tumorigenesis. The promoter of WISP-1 was cloned and shown to be activated by both Wnt-1 and β-catenin expression. TCF/LEF site...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xu, Lifeng, Corcoran, Ryan B., Welsh, James W., Pennica, Diane, Levine, Arnold J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316421/
https://ncbi.nlm.nih.gov/pubmed/10716946
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