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Control of the Intracellular Redox State by Glucose Participates in the Insulin Secretion Mechanism

BACKGROUND: Production of reactive oxygen species (ROS) due to chronic exposure to glucose has been associated with impaired beta cell function and diabetes. However, physiologically, beta cells are well equipped to deal with episodic glucose loads, to which they respond with a fine tuned glucose-st...

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Detalhes bibliográficos
Main Authors: Rebelato, Eduardo, Abdulkader, Fernando, Curi, Rui, Carpinelli, Angelo Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164208/
https://ncbi.nlm.nih.gov/pubmed/21909396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024507
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