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Hysteresis-Based Mechanism for the Directed Motility of the Ncd Motor

Ncd is a Kinesin-14 family protein that walks to the microtubule's minus end. Although available structures show its α-helical neck in either pre- or post-stroke orientations, little is known about the transition between these two states. Using a combination of molecular dynamics simulations an...

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Autors principals: Lakkaraju, Sirish Kaushik, Hwang, Wonmuk
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164182/
https://ncbi.nlm.nih.gov/pubmed/21889447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.07.017
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