Mitochondrial translocation of Nur77 mediates cardiomyocyte apoptosis

AIMS: The cascade of events leading to compromised mitochondrial integrity in response to stress is mediated by various combinatorial interactions of pro- and anti-apoptotic molecules. Nur77, an immediate early gene that encodes a nuclear orphan receptor, translocates from the nucleus to mitochondri...

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Hlavní autoři: Cheng, Zhaokang, Völkers, Mirko, Din, Shabana, Avitabile, Daniele, Khan, Mohsin, Gude, Natalie, Mohsin, Sadia, Bo, Tao, Truffa, Silvia, Alvarez, Roberto, Mason, Matt, Fischer, Kimberlee M., Konstandin, Mathias H., Zhang, Xiao-kun, Heller Brown, Joan, Sussman, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Basic Science
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164102/
https://ncbi.nlm.nih.gov/pubmed/21228009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehq496
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