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Heparin Protects Against Septic Mortality via ApoE-antagonism
BACKGROUND: Apolipoprotein E (apoE), a component of plasma lipoproteins, increases septic mortality in a rodent model of sepsis, presumably by enhancing lipid antigen presentation to antigen-presenting cells via the LDL receptor (LDLR). Downstream, this culminates in Natural Killer T (NKT) cell acti...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3163763/ https://ncbi.nlm.nih.gov/pubmed/21741028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjsurg.2010.10.017 |
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